Hormone Therapy Health Risks

Hormone Therapy Health Risks

A new study evaluated the health risks and benefits of estrogen and progestin therapy and found an increased risk of fatal and nonfatal illnesses (malignancies).

Researchers from the University of North Carolina, Chapel Hill, reported that the Women's Health Initiative (WHI) trial of estrogen plus progestin was stopped early, after a mean of 5.6 years of follow-up, because the overall health risks of hormone therapy exceeded its benefits.

The study analyzed health outcomes three years (mean 2.4 years of follow-up) after the intervention was stopped.

The intervention phase was a double-blind, placebo-controlled, randomized trial of estrogen plus progestin (conjugated equine estrogens 0.625 milligrams daily plus medroxyprogesterone acetate 2.5 milligrams daily) in 16,608 women aged 50-79 years. The post-intervention phase commenced July 8, 2002 and included 15,730 women.

The primary end points were coronary heart disease and invasive breast cancer. A global index summarizing the balance of risks and benefits included the two primary end points plus stroke, pulmonary embolism, endometrial cancer, colorectal cancer, hip fracture and death due to other causes.

The study found that after the intervention, cardiovascular risk was comparable by initial randomized assignments: 1.97 percent (annualized rate) in the hormone therapy group (343 events) and 1.91 percent in the placebo group (323 events).

The researchers observed a greater risk of malignancies in the estrogen plus progestin group than in the placebo group (1.56 percent vs. 1.26 percent). More breast cancers were diagnosed in women who had been randomly assigned to receive hormone therapy vs. placebo (0.42 percent vs. 0.33 percent) with a modest trend toward a lower hazard ratio during the follow-up after the intervention.

All-cause mortality was somewhat higher in the estrogen plus progestin group than in the placebo group (1.20 percent vs. 1.06 percent).

The global index of risks and benefits was unchanged from randomization through March 31, 2005, indicating that the risks of estrogen plus progestin therapy exceed the benefits for chronic disease prevention, reported the researchers.

The increased cardiovascular risks in the women assigned to hormone therapy during the intervention period were not observed after the intervention.

The study authors concluded that a greater risk of fatal and nonfatal malignancies occurred after the intervention in the estrogen plus progestin group and the global risk index was 12 percent higher in women randomly assigned to receive conjugated equine estrogens plus medroxyprogesterone acetate compared with placebo.

Integrative therapies with good scientific evidence in the treatment of menopause include calcium, sage and soy.

Calcium is the nutrient consistently found to be the most important for attaining peak bone mass and preventing osteoporosis. Adequate vitamin D intake is required for optimal calcium absorption. Adequate calcium and vitamin D are deemed essential for the prevention of osteoporosis in general, including postmenopausal osteoporosis. There is a link between lower dietary intake of calcium and symptoms of premenstrual syndrome. Calcium supplementation has been suggested in various clinical trials to decrease overall symptoms associated with PMS, such as depressed mood, water retention and pain.

Sage (Salvia officinalis) may contain compounds with mild estrogenic activity. In theory, estrogenic compounds may decrease the symptoms of menopause. Sage has been tested against menopausal symptoms with promising results.

Soy (Glycine max) products containing isoflavones have been studied for the reduction of menopausal symptoms such as hot flashes. The scientific evidence is mixed in this area, with several human trials suggesting a reduced number of hot flashes and other menopausal symptoms, but more recent research reporting no benefits. Overall, the scientific evidence does suggest benefits, although better quality studies are needed in this area in order to form a firm conclusion.

Integrative therapies with fair negative evidence in the treatment of menopause include boron, evening primrose oil and wild yam.

Boron is a trace mineral found in soil, water and some foods. It has been proposed that boron affects estrogen levels in post-menopausal women. However, preliminary studies have found no changes in menopausal symptoms.

Available studies do not show evening primrose (Oenothera biennis) oil to be helpful with these potential complications of menopause. Small human studies do not report that evening primrose oil is helpful for the symptoms of PMS.

Despite popular belief, no natural progestins, estrogens or other reproductive hormones are found in wild yam. Its active ingredient, diosgenin, is not converted to hormones in the human body. Artificial progesterone has been added to some wild yam products. The belief that there are hormones in wild yam may be due to the historical fact that progesterone, androgens and cortisone were chemically manufactured from Mexican wild yam in the 1960s. From Natural Standard

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Some Favourite Videos I had Posted from 2006

Some of my favorite videos:
Sep 12 God’s Loving Promises
Sep 12 Testimony of Wagdi a former Muslim.wmv
Sep 12 Under Cover Mosque- Birmingham- UK.flv
Aug 15 Mountain Stream Relaxation Video
Aug 15 Amazon Rainforest Relaxation Video
Aug 12 Truth about islam from an ex-muslim lady
May 14 Exploring the Criminal Mind: Murder/Suicide
May 14 The Psychology of the Heart
Feb 22 Brain Mind Lecture 2: Left Hemisphere, Vision, Audition, Language, BrainMind.com
Feb 22 Brain Mind Lecture 1: Lobes of the Brain, Limbic System, Language, Consciousness
Feb 21 Stephen Hawking, Black Holes, and The Creator
Feb 19 Yoga warm- up sun salutation exercise-one of the best clips
Feb 17 Carl Sagan on Human Brain
Feb 17 Maximise the Power of Your Brain – Tony Buzan MIND MAPPING
Feb 10 EFT Emotional Freedom Technique ( For Stress Reduction)
Feb 10 EFT Emotional Freedom Technique
Feb 8 Psychiatry REVEALED!!
Feb 8 Psychiatry vs. Psychology
Jan 7 The Alternative Medicines-Part 2
Jan 7 The Alternative Medicines-Part 1
Dec 30 Dinner Etiquette
Dec 30 Deep Meditation using tested sounds and colour
Dec 9 Counselling 5- Solution Focused Therapy
Dec 9 Counselling 4- Cognitive Behaviour Therapy
Dec 9 Counselling 3- Behaviour Therapy
Dec 9 Counselling 2- Gestalt Therapy
Dec 9 Counselling 1- Person Centred Therapy
Oct 3 LTTE attack in Anuradhapura .wmv
Sep 3 Prof.Lakshman Madurasinghe
Aug 27 “DNA and the Brain” – Dr. James Watson speaks at Google
Aug 27 Creativity and Innovation: Larry Keeley
Aug 27 The Origin of the Human Mind: Insights from Brain Imaging and Evolution
Aug 27 Brain Development
Aug 26 God
General Blog

Some Favourite Blogs From 2006

A Collection of Blogs from 2006
Mar 22 Short Inspirational Movies
Mar 16 10 HARD Ways to Make Your Life Better
Mar 12 20 Stress Fixes for Better Sleep
Mar 1 Basics of Counselling – A 5 part series
Feb 22 Contact Them Affiliate Programme- Please Click on the link below
Feb 21 Danger – Proof that American Economy & Dollar WILL Collapse
Feb 21 10 of the Weirdest Facts about Former American Presidents
Feb 19 The Psychology of Sarcasm
Feb 16 What Kills More Than 8,000,000 People Every Year?
Feb 15 20 Things I’m Glad Life Taught Me
Feb 9 Over 500 Selected Websites
Feb 6 10 Accidental Inventions that Changed the World
Feb 3 Some Useful HR Resources
Feb 1 The Power of Spontaneity and How to Wield It
Jan 29 Tips for a Better Life
Jan 28 Murphy’s Lesser Known Laws
Jan 26 An Essay By Einstein
Jan 25 The Psychology of Success
Jan 23 7 Powerful Steps to Actually Getting Stuff Done
Jan 23 Can You Tell a Fake Smile From a Real One?
Jan 21 Train Your Eyes to See Color, Again
Jan 21 The Science of Sleep (why scientists are still in the dark)
Jan 19 The Hidden Force of Fragrance
Jan 18 Top 100 Funny Quotes
Jan 18 The 7 Spiritual Laws of Success
Jan 17 BBC- Reith Lectures-Very Useful Resource
Jan 17 This week on TED.COM : Design and building -Watch them
Jan 17 What are gravitational waves
Jan 16 NEWSWEEK.COM: “Mind Reading Is Now Possible” (78% accurate.)
Jan 16 Why do we behave the way we do ?
Aug 7 Torture Resources
Aug 1 Electrodes rouse man in coma-like state
May 19 Mental Development Similar Among Boys, Girls
May 13 Evaluating a psychological profile of a serial killer
May 13 Understanding torture and its effects
May 13 Resources on Trauma- Sidran Institute
May 13 PSYCHOLOGY BOOKS Recommended by American Psychological Association
May 8 Emotion in Mind
May 1 People’s SAARC- 2007-New Delhi
Apr 29 Scientists ‘reverse’ memory loss
Mar 4 Loving with all your … brain !!
Feb 22 Mental Health Archive
Feb 21 Mind Interactives From BBC
Feb 20 What is EMDR?
Feb 20 Self Improvement And Motivation- Searchable Archive
Feb 18 Mindfulness-based Cognitive Bahaviour Therapy
Feb 18 Human Brain Creates New Cells – Latest News
Feb 17 Science of The Heart: Exploring the Role of the Heart in Human Performance
Feb 16 Alexander Technique- Here are some resources to explore
Feb 16 BALANCING MIND AND BODY TO AVOID CANCER
Feb 15 Reith Lectures-BBC and TED Talks for some valuable inputs
Feb 14 BODY AND MIND -BBC Links
Feb 13 Phantoms in the Brain
Feb 7 Psychiatric Drugs- Cure or Quackery ?
Jan 19 Post Traumatic Stress Disorder (PTSD)
Jan 17 Let us move towards WELLNESS !! Also Chakra Energy
Jan 16 The Mind As Medicine
Jan 14 All you need to know about Sri Lanka- The Paradise Island
Jan 14 AYURVEDA IN SRI LANKA – What is Ayurveda & Where to get services
Jan 14 Love Is Real Medicine
Jan 13 PSYCHOLOGICAL DISORDERS – Bach flower, Homeopathy, Hypnosis
Jan 11 Using Visualization for Learning
Jan 7 Importance of Having Breakfast!
Jan 5 Integrative Medicine Newsletter
Jan 5 Health Week In Review
Jan 3 Did Acupuncture Originate In Sri Lanka ? 2001 News Item
Dec 24 EVIDENCE FOR THE EXISTENCE OF ANOTHER STATE OF REALITY
Nov 18 How strong is your MIND-BODY connection
Nov 3 Study Suggests New Health Benefits of Red Wine
Nov 1 Drinking coffee ‘is good for the heart’
Oct 26 I have learned…….
Oct 23 Happiness is a Voyage
Oct 16 Millennium Development Goals- Downloadable Tool Kit
Oct 15 UNIVERSAL DECLARATION OF HUMAN RIGHTS(UDHR)
Oct 14 Bar Association Journal Article-May 2004- THERAPEUTIC JURISPRUDENCE
Oct 13 THE MILLENNIUM DEVELOPMENT GOALS-UN
Oct 12 Lateral thinking- here are the answers
Oct 8 PSYCHOLOGY RESOURCES
Oct 8 Lateral Thinking
Oct 7 How to Prevent Executive Derailment
Oct 4 Snoring: It May Be More Serious Than It Sounds
Sep 29 Overachievement !!
Sep 28 Cambridge University Findings on How Our Brains Operate
Sep 26 The Healing Touch
Sep 23 Rich Vs Poor
Sep 23 Who moved my Cheese
Sep 15 A Study Of Ecclesiastes- 11 & 12- FINAL
Sep 12 Are you a type ” D” ?
Sep 6 Stay Positive in the Face of Negativity
Sep 5 A Study Of Ecclesiastes – 9 & 10
Sep 5 The Quality of Fat in Your Diet May Be More Important for Your Heart Than the Quantity
Aug 31 Antioxidants: Antidote to Aging?
Aug 29 Adult Obesity
Aug 29 What Time Should You Exercise?
Aug 29 A Study of Ecclesiastes – 8
Aug 27 Hospitals Add Alternative Medicine
Aug 22 Old timers should enjoy this (newcomers too) Spiritual songs
Aug 20 JUDGEMENT DAY (Salvation Video)
Aug 20 The Thief (Video)
Aug 19 In her own words: Living with Parkinson’s disease
Aug 17 A Study of Ecclesiastes- 6 & 7
Aug 12 A study of Ecclesiastes- 4 & 5
Aug 6 Parkinson’s Disease
Jul 30 Mind -Body Walking: Medicine for Body and Spirit
Jul 29 Cancer Fatigue: It’s more than just being tired
Jul 24 Believe in Order to See
Jul 19 The Key to Effective Time Management
Jul 17 Musical Cures For Modern Ailments
Jul 15 Rheumatoid Arthritis
Jul 13 Stress Relievers
Jul 13 Eating Fish Protects Your Eyes
Jul 13 High Blood Pressure -HBP
Jul 11 Are you Taking Drugs You Don’t Need
Jul 10 Why Sleep is important for Memory
Jul 10 Hypnosis: Does it Work ?
Jul 9 ASTHMA CURE
Jul 6 Top 10 Reasons God Created Eve
Jul 6 Progress in Stroke Prevention
Jul 4 ALTERNATIVE MEDICINE RESOURCES
Jul 4 How to survive a Heart Attack when alone- A medical hoax !!
Jul 4 How to correctly identify a stroke- American National Stroke Association
Jul 4 Stroke
Jul 3 How I became my own Grandfather
Jul 3 Balancing Inner and Outer Healing
Jul 1 Living with Leukemia
Jun 27 Aromatherapy
Jun 27 Be Thankful in life Col 3: 12-17
Jun 23 Danger from excessive texting on phones
Jun 22 NET or Neuro -Emotional Technique
Jun 16 Pride in many Disguises;Prov 16:18
Jun 13 HOW TO BEGIN EACH DAY Psalm 57: 1-11
Jun 12 BEING VS DOING
Jun 9 WILL THIS STUDENT PSALM HELP ?
Jun 3 Adam and Eve
General Blog

Labour Law- Key Cases

Unfair dismissal

Airbus UK v Webb
(unreported, EWCA Civ 49, 7 February 2008, CA)

Five employees were found guilty of misconduct for misusing company time (by watching television during working hours). Four employees were given final written warnings, but one employee was dismissed. This was because he had been given a final written warning for a similar act of misconduct thirteen months earlier. The warning had expired three weeks before the second act of misconduct. The employee brought an unfair dismissal claim which was upheld by an employment tribunal and the Employment Appeal Tribunal (EAT).

The Court of Appeal (CA) over turned the decision of the EAT, and held that the employee was not unfairly dismissed because the employer had relied on an expired warning. In a previous case Diosynth Ltd v Thomson [2006] IRLR 284 CS it was held that a spent warning should be ignored for all purposes. However the CA said that Diosynth was only authority for stating that it would be unreasonable for an employer to rely on an expired warning as a principle reason for dismissal. The CA also stated that under Diosynth the expired warning ‘tipped the balance’ in favour of dismissal (as other factors taken together would not have justified dismissal), but in the present case the employee was dismissed mainly because of his misconduct and not because of the expired warning.

Implications for employers:

  • Employers who take expired warnings into account before implementing a dismissal will not necessarily have unfairly dismissed the employee. However, such a practice is still very risky.
  • As a matter of best practice employers should not rely on expired warnings, especially not as the principal reason for dismissal.
  • If an employer does rely on an expired warning and there is also underlying misconduct, it may be reasonable to take the warning into account as well -provided that the subsequent misconduct is sufficient to warrant dismissal in its own right.

Stress

Deadman v Bristol City Council
[2007] IRLR 888 CA

A council employee was accused of sexual harassment. The council’s policy was that all harassment claims should be sensitively dealt with and investigated by a three-person panel. However, the investigation was carried out by a two-person panel and the employee raised a grievance. The council upheld his grievance, but left a letter on his desk informing him that the claims would be investigated by a three-person panel. The employee went off sick with depression and did not return to work. He then brought a personal injury claim. He argued, based on several Council documents that were not in his employment contract, that the Council had a contractual obligation to act sensitively and had failed to do so by merely leaving the letter on his desk telling him that the matter would be re-investigated.His claim was upheld by the High Court which held that the council was in breach of the employment contract and that it was reasonably foreseeable that such a breach would case a psychiatric illness.

This decision was overturned by the Court of Appeal which held that the use of a two-person panel was in breach of contract but it was not reasonably foreseeable that this would cause the employee a psychiatric illness.

Implications for employers:

  • Employers will only be vulnerable to such claims if the harm suffered by the employee was a reasonably foreseeable result of the employer’s actions.
  • At the very least, employers should follow their own policies and procedures and any statutory procedures carefully.
  • If employers implement contractual procedures, very careful attention should be paid to the wording as there may be a contractual term that the employer must follow its published procedure to the letter in the investigation of any complaints made against the employee.
  • Employers will always be subject to the implied obligation of mutual trust and confidence, and the duty to take reasonable care, but any damage suffered by an employee must still be reasonably foreseeable.

Sex discrimination

Madarassy v Nomura International plc 
[2007] IRLR 246, CA)

The Court of Appeal held that an employer is not obliged to prove that an employee was treated fairly once she had established that as a pregnant woman she had been discriminated against.

The employee, a banker, who claimed that she had suffered discrimination while pregnant went on maternity leave in March 2001. She also claimed that when she was on maternity leave she was not informed that her department was being restructured which put her at a disadvantage in the restructuring and redundancy process. In November 2001 she was dismissed for redundancy. She brought £1 million proceedings for discrimination citing 33 allegations. These allegations were dismissed by the employment tribunal and Employment Appeal Tribunal, apart from one concerning the employer’s failure to carry out a health and safety assessment relating to her pregnancy.

The Court of Appeal had to decide what degree of unfair behaviour an employee was required to establish to transfer the burden of proof onto the employer to prove that it did not act unfairly. The Court of Appeal concluded that there had to be more than a set of circumstances where the tribunal could ‘conclude’ discrimination. Differences in status and treatment were not sufficient to establish a prima facie case of discrimination. It also ruled that the employer was correct in not carrying out a risk assessment as there was no evidence from the employer that her working conditions put her at risk. The employee is intending to appeal to the House of Lords.

Implications for employers:

  • This is an important decision for employers who are now less exposed to sex discrimination claims in such circumstances as it will be harder for employees to establish that discrimination took place.
  • In cases under the Sex Discrimination Act 1975 the employee always has to prove a prima facie case of sex discrimination. Previous cases have set this threshold at a very low level. The level now appears to be higher.
  • However if a similar dismissal does take place the timing i.e straight after return from maternity leave will not of itself show a prima facie case of discrimination against the employer.
  • There must be some other link in addition to the timing which suggests there may be a discriminatory reason for the dismissal, thereby enabling the employee to get the claim off the ground.
  • An employee wishing to claim discrimination also now needs to show more than mere differences in status or treatment to force the employer to show that they have not discriminated. There needs to be something more than that.
  • Despite this decision obviously the safest, most cautious, course of action for employers is always to try and avoid dismissing employees (or selecting them for redundancy) whilst they are pregnant, or during/upon return from maternity leave.

General Blog Law

New Book-Employment Law

An Introduction for HR and Business Students

 

 

Kathy Daniels

 

Pages: 288   Published: March 2008

 
ISBN: 1843981882
ISBN13: 9781843981886
 

Price: £24.99

 


Description

 
 

Employment Law can be a challenging subject for students who have no prior experience of studying or working with Law.

Employment Law: An Introduction for HRM and Business Students is an ideal text for those business students on undergraduate and postgraduate courses who are taking a module in Employment Law. It covers a comprehensive range of topics enabling students to gain a solid understanding of the key principles of the subject. The engaging, authoritative writing style and range of learning features make this a refreshingly accessible and student-friendly read.

This new edition has been thoroughly updated, and includes expanded coverage of the impact of EU Law, and Discrimination Law including ageism, sexual orientation, religious belief, harassment and disability.

Each chapter includes summaries of topical and relevant cases, direction to key sources of legal information and suggestions for further reading while covering the CIPD Standards for the Employment Law elective on the Professional Development Scheme (PDS).

This text includes a range of case studies, tasks and examples to consolidate learning and includes a brand new section on Employment Law study skills to help students get to grips with how to access and read law reports, understand the sources of the law, find and use up-to-date legal information (particularly websites) and how to prepare for exams and written assignments.

  
 

Contents

 

Cases referred to in this book
Legislation referred to in this book
Preface
Acknowledgements

Studying Employment Law
The Formation of Employment Law
The Employment Tribunals and Employment Appeal Tribunal
Contract of Employment
Atypical Contracts and the Variation of Contracts
Individual Protection Rights
Discrimination (1)
Discrimination (2)
Termination of Employment (1)
Termination of Employment (2)
Trade Union Legislation
Privacy and Confidential Information
Health and Safety Legislation

Useful Websites
Index.

  

 

About the author(s)

 

Kathy Daniels

Kathy teaches at Aston Business School and is a tutor for ICS Ltd in Employment Law and related topics. She is also a tutor on the Advanced Certificate in Employment for the Chartered Institute of Personnel and Development. She is a fellow of the CIPD. She is a lay member of the Employment Tribunals, sitting in Birmingham. Prior to these appointments she was a Senior Personnel Manager in the manufacturing sector. Kathy has also written for a number of other CIPD texts including ''Employee Relations in an Organisational Context'', ''Equality, Diversity and Discrimination'' with Lynda Macdonald, and the forthcoming textbook from the Aston Centre of Human Resources, ''Strategic Human Resource Management: Building Research-Based Practice''.

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